Does CBD and Cortisolination Work in Combination?
A recent study from Washington University found that CBD and cortisol levels differ in individuals who are genetically predisposed to breast cancer. CBD is an endocannabinoid that when combined with cortisol, promotes the body’s ability to heal itself.
Cortisol is a stress hormone that are usually found in high levels in older people and women who are premenopausal, and in low levels in young and middle-aged men and women.
The study was funded by a grant from the National Institute on Aging (NIA) and the National Cancer Institute (NCI). CBD has been shown to help decrease the inflammatory response in a mouse model of breast cancer, but it has not been studied in humans.
In humans, the use of inhibitors of the enzyme N-methyl-D-aspartate (NMDA) receptor, which controls the excitatory effects of NMDA, is known to increase glucocorticoids and enhance apoptosis, or programmed cell death.
Activation of the NMDA receptor triggers the release of cortisol. But CBD has shown to inhibit this process in cells from women who have been treated for breast cancer, but not in those who had not been treated.
Epigenetics is the term that refers to the way in which our genes affect our diseases and other chronic disease states. The endocannabinoid system is part of the epigenetic system. Epigenetics refers to how our genes express themselves in an individual.
Cortisol and CBD
Cortisol and CBD can be included in the diet as possible ways to lower cholesterol and inflammation, or their natural presence can help to reduce the secretion of inflammatory chemicals by the body. What this means is that the good things that are already there in our food supply can be targeted in a positive way to fight cancer, including CBD and cortisol.
CBD may also be helpful in people with ulcerative colitis, Crohn’s disease, psoriasis, and fibromyalgia. It may be possible to combine the CBD with a magnesium supplement to be effective against both conditions. Meniere’s disease and even bipolar disease, which involve disturbances in the balance of chemicals in the brain, may benefit from CBD.
One of the beneficial properties of CBD is its potential to improve the function of nerve cells, especially those involved in mood and behavior. It is a natural antidepressant and could help control depression in a number of disorders, including Alzheimer’s disease, schizophrenia, and Tourette’s syndrome. However, it has not been studied in controlled clinical trials.
Do you know Melatonin?
Melatonin has many benefits. It may be useful for people suffering from insomnia, and it could possibly reduce fatigue and improve sleep, as well as improving eyesight.
The study at Washington University found that Melatonin improved indicators of inflammation in the blood vessels, in addition to reducing the number of abnormal cells that produced inflammation.
In a clinical trial involving more than 300 participants, researchers have found that people who took CBD combined with melatonin had fewer signs of inflammation and did not develop problems with sleep.
In the same study, patients taking CBD combined with caffeine for an extended period of time reported improvements in sleep. Of the individuals taking CBD, those who took melatonin also improved their sleep pattern.
For the most part, the effect of Melatonin on inflammation was stronger than that of CBD. Melatonin has some advantages over CBD in the reduction of inflammation, including its ability to improve sleep.
CBD and sleep quality
When CBD was taken alongside melatonin in the same treatment group, the effect was the same. This suggests that while CBD is effective for reducing inflammation, it may not be useful in a combination with melatonin.
If you are suffering from cancer or any other chronic disease, these studies could help you make an informed decision about whether CBD and melatonin might be beneficial to you.
There is much work to be done in finding the best combination of the two compounds. and while this study was a small, preliminary one, it is still thought that future research should explore the possibility of combining CBD and melatonin, as well as using CBD to help reduce inflammation.